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The increase in lactate that we detected points towards a defect in oxidative energy metabolism, but this conclusion must be treated cautiously given the difficulty of measuring lactate in the presence of the much larger and broader macromolecule (MM) resonance at ~1.35 ppm, with the lactate signal being a small shoulder on that peak (Fig

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Ipamorelin is a pentapeptide five amino acids with the sequence Aib-His-D-2-Nal-D-Phe-Lys-NH and a molecular weight of 711.86 g/mol, first described in 1998