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Description

Common gastrointestinal side effects (nausea, bloating) may make rich or sweet foods less appealing during treatment

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Compounded PT-141 is not an FDA-approved finished product

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In a post hoc analysis of the SUMMIT trial, the decrease in estimated blood volume seen in participants treated with tirzepatide was significantly correlated with decreased blood pressure, lower microalbuminuria, improved KCCQ-CSS, and greater 6-min walking distance [85]

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One proposed mechanism involves the effect of GLP-1 receptor agonists on glucose metabolism

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The full Phase 3 programme, called TRIUMPH, is still running

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