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The Endocrine Society's guidelines for anti-androgen therapy recommend gradual withdrawal when medications have been used for more than 6 months 4

Its also different from other popular antidiabetic medications, such as metformin

Reviewed by the PeptideMind Team Updated July 15, 2026 Ipamorelin Dosage Guide, Benefits & Side Effects Ipamorelin selectively triggers GH release without raising cortisol or prolactin, supporting fat loss, sleep, and recovery

DSIP works through subtle neurochemical modulation rather than brute-force sedation

This is important and our clinical governance team advises you to pay attention to the side effects