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Semaglutide GLP-1 injections help people lose a significant amount of weight quickly

Patients with diabetes, cardiovascular disease, or other chronic conditions should consult healthcare providers before initiating new exercise programs

Potential downsides include a slower onset of significant weight loss compared to tirzepatide and gastrointestinal side effects, particularly nausea during the first month, that can be challenging when you are already dealing with fatigue and disrupted eating patterns

However, despite GLP-1 agonists higher efficacy, the higher cost makes them not cost-effective [61] in some analyses when compared to older, less expensive alternatives

Week 2: Noticing Early Changes By the second week, patients often experience their GLP-1 results first week , such as a slight drop in weight, improved digestion, and fewer cravings