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doi: 10.1186/s12974-020-02056-0 64

Medical oversight remains crucial, particularly for individuals with complicated backgrounds or those on other hormone therapies

Regarding the glucuronidation of morphine, two metabolites are formed, morphine-3-glucuronide, which is the major metabolite (45-55%) but inactive and morphine-6-glucuronide (20-30%), which is the more potent analgesic than its parent compound (Christrup, 1997)