Upon transfection or transduction with genes encoding for one or multiple drug metabolizing enzyme genes, HepG2 cells have been shown to be a valuable model system to study the role of bioactivating enzymes in the cytotoxicity of toxicants (Vignati et al., 2005
You start at 2.5 mg for the first month, then gradually increase every four weeks based on tolerance and results
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Formulations often include B vitamins and lipotropic compounds such as methionine, inositol, choline, and vitamin B12
