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Trans -acting lncRNAs may regulate gene expression by interacting directly with DNA or chromatin complexes, serve as a scaffold to assist nuclear transcription and RNA processing, or control intracellular trafficking, cell-cell signaling and protein regulation through interaction with different macromolecules including proteins and RNA [2]

Another epigenetic regulator of interest is JMJD3 (also known as KDM6B), a histone H3K27 demethylase that plays crucial roles in both vascular and cancer biology

Growth hormone secretagogues

Hanley MR, Lee CM, Michell RH, Jones LM

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