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10.1038/414813a 2 BuseJ

Earlier studies on semaglutide established that this kind of medication can do more than lower glucose, with reductions in major adverse cardiac events seen in some trial populations

Retatrutide is an investigational peptide currently in clinical trials that builds on the success of GLP-1 and GIP therapies

However, our study found that subjects taking NSAIDs (a list of these medications is found in Supplemental Table 3) simultaneously with GLP-1 M collectively showed an overall weaker response to GLP-1 M treatment (Table 4, FDR = 5.16E-03)