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We obtained the entries for the responsible metabolic enzymes from the BRaunschweig ENzyme DAtabase (BRENDA) database 81 and extracted their allosteric effector (activator and inhibitor) information and inhibitory half-saturation constants (K i ) values, as reported for Homo sapiens , Mus musculus , and Rattus norvegicus
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Bardoxolone for CKD: the paradox of confusion and dogma
This study highlights the coordinated role of epigenetic dysregulation, oxidative stress, and trace element imbalances in the pathogenesis of PCOS
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