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Archived from the original on November 3, 2012

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The capability of Sp to replenish reduced glutathione levels was further tested in neuronal cells exposed to MPP + , the toxic bioactivation product of MPTP known to induce Parkinsonian phenotype in animal models 1

Long-term administration of melatonin, whose pineal secretion decreases with age, was highly effectively at preventing age-dependent impairment of redox status in various tissues and cells 12