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What symptoms to expect and how long they last Mild symptoms (usually resolve on their own) These are the most common and usually fade within a few days to a week: Nausea Vomiting Diarrhea or constipation Abdominal pain or cramping Headache Loss of appetite Fatigue Injection-site soreness Because Mounjaro sticks around for about 5 days, expect symptoms to linger 5 to 7 days rather than clear in 24 hours

Most cases resolve within the first 24 weeks as the body adjusts

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