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In the recent time, and by multivariable-adjusted analysis, factors such as female sex, diabetes, liver disease, proton pump inhibitors, abdominal pain, increased age, body mass index (BMI), and liver stiffness were associated with gallstone disease, while non-Hispanic Black and non-Hispanic Asian race and alcohol were inversely associated
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It has been described for roGFP1-iL that the insertion C147CL and the substitution H148S lower the thermodynamic stability of the inter-strand disulfide C147C204 resulting in a less negative E of the sensor (Lohman and Remington, E roGFP2-iL was determined through titration with LA/DHLA
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