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SOUL was a multicentre, international, randomised, double-blind, parallel-group, placebo-controlled, phase 3 cardiovascular outcomes trial with 9,650 patients with type 2 diabetes and established cardiovascular disease (CVD) and/or chronic kidney disease (CKD)

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This is concerning as SLE patients may already be in a hypercoagulable state, and development of pulmonary emboli (PE) and deep vein thromboses (DVT) are common complications of COVID-19 disease (21)