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We showed that the antibody Fab fragment (Fab 3F52) blocked the GLP-1 binding site of the ECD directly and thereby acts as a competitive antagonist of native GLP-1

The advisory emphasises that "decisions about how quickly or slowly to titrate therapy should be guided by an individual's needs." This requires precise, ongoing body composition data, not just weight

GLP-1 (Glucagon-Like Peptide-1): GLP-1 plays a key role in appetite regulation by promoting satiety and reducing hunger signals

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