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It may affect other organs such as the central nervous system through ectopic ova deposition, and lead to cognitive and physical impairment - especially among children ( Schistosomes co-exist in immunocompetent hosts for decades since they adapt, modulate, and evade cellular and humoral immune defense mechanisms though with parasite species-specific differences ( Host Immunity Upon infection in humans, the immune system is confronted with multiple moieties exposed during the various lifecycle stages
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Prevalence and Age: What the Numbers Tell Us ED prevalence climbs with age, driven by cumulative vascular risk, hormonal shifts, medication burden, and chronic disease
Bibcode:2001PlMed..67..306D
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