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This process can be initiated by iron-catalyzed Fenton chemistry, in which hydroxyl radicals (OH) generated from H 2 O 2 trigger a self-propagating lipid peroxidation chain reaction

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These include: Nausea (most frequent, often transient) Vomiting and diarrhoea Constipation Abdominal discomfort or bloating These symptoms typically diminish over 48 weeks as tolerance develops

Abstract Background To conduct a real-word-study-based cost-effectiveness analysis of a GLP-1 receptor agonist (GLP-1RA) versus insulin among type 2 diabetes patients requiring intensified injection therapy and a systematic review of cost-effectiveness studies of GLP-1RAs versus insulin