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doi: 10.1002/ptr.6218 63 ParkWSKwonOYoonTJChungJH

Efficacy and safety of sildenafil added to pirfenidone in patients with advanced idiopathic pulmonary fibrosis and risk of pulmonary hypertension: a doubleblind, randomised, placebocontrolled, phase 2b trial

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For this reason, DSIP is most often studied in the context of sleep architecture, stress regulation, and neuroendocrine balance rather than as a pure sleep-onset agent