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Most GLP-1 receptor agonists are administered via subcutaneous injection , typically once weekly (semaglutide, dulaglutide) or once daily (liraglutide), depending on the specific agent

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1 Like most complex genomic regulatory systems, Nrf2 (nuclear factor erythroid 2-related factor 2) is sequestered in the cytoplasm until it is able to translocate into the nucleus, where it forms a heterodimer with MAF (another transcription factor) and binds to the promoter region of genes containing an antioxidant response element (ARE) sequence

Ethics approval The experimental protocols were performed in accordance with the National Institutes of Health Guide for the Care and Use of Laboratory Animals, and were approved by Animal Ethics Committee of Guangxi Medical University (Approval Number: 2023-E369-01)