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doi: 10.3390/biology13110936

Biodistribution and therapeutic effects in subcutaneous osteosarcoma mouse model The therapeutic properties of the nanoparticles were further studied inside an 143B tumor-bearing immunodeficient nude mouse model (Fig

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Grx isoenzymes have been shown to metabolize both glutathionylation and deglutathionylation reactions and are controlled by the overall redox state of the GSH pool, where a more oxidized (GSSG) environment favors glutathionylation while restoration of reduced (GSH) levels steers deglutathionylation [45]

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