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If youre managing Polycystic Ovary Syndrome (PCOS), youve likely heard about the "big two" in the world of GLP-1 medications: Semaglutide and Tirzepatide

Demand for semaglutide, sold under the brand names Ozempic, Rybelsus, and Wegovy, as well as another GLP-1 drug called tirzepatide (more commonly known as Mounjaro and Zepbound) soon soared, with one poll published in May finding that one American adult in eight had been prescribed a GLP-1 at some point

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Improvements in glycaemic control 6 months after treatment initiation were sustained at 12 months, whereas maximum weight loss benefits required at least 12 months to become apparent

Inhibition of mitochondrial (etomoxir) and peroxisomal (thioridazine) fatty acid oxidation revealed that each organelle contributes to approximately half of acetyl-CoA produced from palmitate in the DKO cells (Supplemental Figure 5G)