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Examples include superoxide dismutase (SOD), catalase, and GSH peroxidases (GSH-Px) a family of cytosolic, mitochondrial, and extracellular enzymes that detoxify lipid hydroperoxides and H 2 O 2 by oxidizing GSH to GSSG
Much of the glutathione gets broken down in the digestive system before it ever reaches the bloodstream
further investigation is needed.60, 61 Of interest, the time course of HPC activation in mice was closely correlated with temporal changes in serum stem cell factor (SCF) after APAP-induced liver injury, suggesting a potential role of SCF in progenitor cell activation.62, 64 Another study reported increased expression of SCF and its receptor c-kit (progenitor cell marker) in liver after APAP overdose in mice
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