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Later that day, FDA announced the resolution of Novo Nordisks semaglutide shortage, which altered the conclusion of our original post and warranted this update

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Clinical research on the FDA-approved branded versions of these active ingredients includes the STEP-1 trial, which demonstrated mean weight reduction of approximately 14.9% with semaglutide over 68 weeks, and the SURMOUNT-1 trial, which showed tirzepatide achieving 1622.5% weight reduction over 72 weeks

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