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Exploring the Interplay between Polyphenols and Lysyl Oxidase Enzymes for Maintaining Extracellular Matrix Homeostasis

The study demonstrated for the first time that quantitative target engagement can be assessed at the GLP1R and GCGR by PET

GLP-1 MKDA: effects of GLP-1 do not survive correction To estimate the hypothesized reward-suppressing effect of GLP-1, we conducted a meta-analysis for negative associations of GLP-1 with reward-related brain responses

Enhancing GLP-1 signaling through GLP-1RAs increased CaMKK2AMPK signaling, which subsequently reduced BACE1-mediated cleavage of amyloid precursor protein (APP) and A generation

Reference: Schijns W, Homan J, van der Meer L, Janssen IMC, van Laarhoven CJHM, Berends FJ, Aarts EO