When to talk to a healthcare provider Only take GLP-1s alongside the guidance of a healthcare provider, and with regular touchpoints where you can talk to that provider about your symptoms
Setting realistic expectations is crucial: weight loss is gradual, with clinical trials showing approximately 15% weight reduction with semaglutide 2.4 mg at 68 weeks and up to 21% with tirzepatide at 72 weeks, though individual responses vary considerably
The most common time to see side effects like these are when you initially start the medication or when you are increasing the dose
Ongoing research is focused on multi-target agonists, oral drugs, and broader therapeutic applications beyond diabetes and obesity, including cardiovascular, kidney, liver, and neurodegenerative conditions
That isnt to say you cant (or shouldnt) stop taking these medications if your side effects are severe