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pretreatment with a high concentration of U50,488 failed to promote KOR uncoupling from G proteins (Li et al., 2002)

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Reduced overall food intake, less fluid, and slower gut motility (how quickly the intestines move) can all stack the deck

Neurofibromas in NF1 are relatively frequent on the trunk, which contrasts with the distribution of peripheral nerve schwannomas, which are more frequent in the extremities [76]