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Theoretically, the two compounds target completely different receptor systems (amylin receptors for cagrilintide, GLP-1/GIP/glucagon for retatrutide), which suggests they could work synergistically without receptor overlap

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The G/D-CuP denoted the unlabeled hydrogel, while the CV-G/D-CuP represented the hydrogel labeled with Crystal Violet dye for enhanced visual observation

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