Nutritional priorities to support GLP-1 therapy for obesity: A joint advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and the Obesity Society, Obesity Pillars
Alcohol consumption measures
In particular, long-term use of non-steroidal anti-inflammatory drugs (NSAIDs) can cause gastric mucosal damage as they can inhibit mitochondrially encoded cytochrome C oxidase I (MT-CO1, also known as COX-1) and block its protective effect on gastric mucosa
In early trials, people also saw benefits beyond weight loss, including: Better blood sugar control (lower HbA1c levels) Reduced blood pressure Improved cholesterol Lower levels of liver fat To learn more about retatrutides wider benefits, see our Retatrutide benefits article How long before retatrutide works Retatrutide tends to start working within 2 to 4 weeks
Semaglutide (Wegovy, Ozempic) aims at one receptor (GLP-1), while tirzepatide (Zepbound, Mounjaro) homes in on two (GLP-1 and GIP)