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MariTide Name: Maridebart cafraglutide (MariTide, formerly AMG 133) Manufacturer: Amgen Current stage: US phase III trial currently underway (MARITIME, NCT06858839) Takeaway: The dual agonist/antagonist action of MariTide could promise higher weight loss with fewer side effects, with dosing at less frequent intervals but more studies are needed
Both doses met all primary and key secondary endpoints
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5 Journal of Internal Medicine (PubMed)Cibinetide improves small-fiber neuropathy symptoms and corneal nerve-fiber measures in early clinical studies
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