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Ali DA, Abdeen AM, Ismail MF, Mostafa MA

This epigenetic regulation involves copper-dependent activation of cellular pathways including enhanced DNA repair, increased antioxidant enzyme production, and stimulation of regenerative processes while simultaneously suppressing inflammatory and destructive gene programs

Particular emphasis is placed on the molecular recognition mechanisms between DAMPs and PRRs (TLRs, NLRs, CLRs and RAGE), and the disease regulatory networks formed by activated key signaling pathways (NF-B, MAPK, inflammasomes and cGAS-STING)

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Its efficacy and relative safety have made it a preferred choice for many healthcare providers and patients