While several metrics of biological aging have been used to demonstrate this link, 8,9 telomere length (TL) has been extensively used to index accelerated aging in MDD 10,11,12 and other chronic somatic diseases, namely cardiovascular disease 13,14,15,16,17 , diabetes 18,19 as well as premature mortality in a meta-analysis 20
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Adjuvant dabrafenib plus trametinib versus placebo in patients with resected, BRAFV600-mutant, stage III melanoma (COMBI-AD): exploratory biomarker analyses from a randomised, phase 3 trial