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1: Diagram of the transport of long-chain fatty acids mediated by L-Carnitine from the cytoplasm into the mitochondrial matrix (modified after [9]) Derived effect on L-Carnitine fat burning Claimed effect: The intake of additional carnitine supplements is said to lead to increased fatty acid burning

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Proc Natl Acad Sci U S A 2007;104:6436-6441

Adults with a BMI of 27 or higher (overweight): You may be eligible if you also have at least one weight-related health condition, such as: Type 2 diabetes High blood pressure High cholesterol These medications are recommended for individuals who have tried losing weight through lifestyle changes but have not achieved significant or sustainable results