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Based on these mechanisms, emerging interventional strategies have been proposed to curb intercellular ferroptotic spread, including: blocking exosome-mediated signal transmission, inhibiting STING pathway activation, and enhancing astrocytic phagocytic and clearance functions

271 Feeding endothelial cell-specific inactivated mice a high-calorie diet improved insulin resistance and decreased fat accumulation, 271 suggesting that the suppression of endothelial p53 could be a new target for the treatment of obese patients with metabolic abnormalities

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Thank you to our sponsors AG1: Eight Sleep: Function: Timestamps 00:00:00 Huberman Lab Essentials