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10.1093/eurheartj/ehy585 111 WhitbourneS

65 Conversely, two studies ( n = 60, 87) combining metformin (5001700 mg/day) with Diane35 for 3 months reported greater reductions in androgens and body fat and better metabolic profiles with the combination treatment, compared with Diane35 alone

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The effect of GLP-1R agonists liraglutide and exendin-4 was examined in vitro on LOVO, CA-77, MCF-7, MDA-MB-231, KPL-1, MB-468, 4TI, BT483, ZR751, LNCap, PC3, ALVA-41, DU145, LNCap, PANC-1, MiaPaCa-2, PANC, CT26, SKOV3, OVCAR3, OVCAR4, A2780, and ES-2 cell lines that are expressed in several cancers including colorectal, pancreatic, thyroid, breast, prostate, ovarian, and colon (Table 1)