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Bodea, F., Bocea, A., and Decea, N

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ArticlePubMed 90

The glucocorticoid-induced leucine zipper mediates statin-induced muscle damage

Total weight loss at 48-68 weeks on the combination is difficult to predict without clinical trial data, but based on individual compound data (retatrutide at 24-28.7% and the additive benefit seen with CagriSema), a reasonable estimate for the combination is 25-35% total body weight reduction in high responders