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Commonly reported adverse events included severe stomach problems, very rapid heartbeat, and serious allergic reactions

On average, patients who took 12 mg doses lost 11.5 lbs, or 5.8% of their body weight, while patients who were administered 36 mg doses lost 15.8 lbs, or 7.6% of their body weight

A commonly referenced low-dose starting point is: Around 1 milligram per kilogram of body weight More broadly, discussions around methylene blue dosing often highlight a low-dose window, since the compound appears to follow a hormetic response where smaller amounts can behave differently from higher concentrations