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It helps relieve or prevent fatigue and may have acted in the anti-inflammatory process by reducing histamine release

Dysautonomia, particularly Postural Orthostatic Tachycardia Syndrome (POTS), frequently co-occurs with Long COVID and ME/CFS

Allergy to Cobalt or any other ingredient in the supplement - These people should not take B complex vitamins

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However, major expert groups have looked at the research and concluded that: The evidence is not sufficient to show that screening every adult without symptoms for vitamin D deficiency clearly improves outcomes such as fractures, heart disease or cancer