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Neuroinflammation and oxidative stress play a role in the pathophysiology of ADHD due to genetic and environmental factors, catecholaminergic dysregulation, and medications used for treatment, all factors which could produce inflammation and oxidative stress, which increases the symptoms and, as a consequence, leads to establishing a vicious circle (Figure 1)

10.1038/s41598-024-65507-1 255 ShihM