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When levels drop due to stress, pollution, poor diet, or ageing, the result often shows up as dull skin, uneven tone, pigmentation, and fatigue

UAE Research has found that by targeting melanocortin receptors in the brain, particularly the melanocortin 4 receptor (MC4R), PT-141 triggers pathways involved in sexual response

Patients with CFS often present an abrupt onset of fatigue, flu-like illness, and exacerbation of fatigue with exertion

However, like most other medical treatments their efficacy would depend on the patient and extent of these hyperpigmentations or scarification processes

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