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The culture media was changed every other day

Gastroenterology 129 , 591608 (2005)

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The E3 ligase tripartite motif 8 targets TAK1 to promote insulin resistance and steatohepatitis

Their work further identified the switch defective/sucrose nonfermentable (Swi/Snf) chromatin remodeling complex as a key regulator of RORt-mediated histone modifications, revealing that Swi/Snf and RORt cooperate to orchestrate the epigenetic activation of Th17 differentiation genes