Moreover, it is employed in the preservation of protein-dithiols by the protein disulfide reductase (glutathione) (EC 1.8.4.2), an enzyme that catalyzes the chemical reaction: This enzyme acts on different substrates, such as insulin, which is inactivated by cleavage of the disulfide bridge, or on protein disulfide, in which the reduction to protein-dithiol restores the catalytic activity, protecting the cell from oxidant stress
J., Weaver, A
Sasi M, Vignoli B, Canossa M, Blum R
Final Thoughts Glutathione is an important antioxidant with well-recognised medical significance
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