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The above data suggest that redox imbalance as a result of repeated treatment with a glutathione synthesis inhibitor (BSO) administered alone or in combination with a DA reuptake inhibitor (GBR 12909) during early postnatal development, may be an important factor reducing the BDNF protein levels or mRNA expression in the frontal cortex and in the hippocampus in adulthood

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Both are essential for normal cell division and successful fertilization

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