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Experimental studies have demonstrated measurable increases in circulating growth hormone and downstream IGF-1 signaling in controlled settings, with preserved natural GH pulsatility and no observed pituitary desensitization at standard research doses [2]

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Poor absorption from IBS, SIBO, or gastritis leads to hormone swings

These pathophysiological alterations trigger pro-inflammatory cytokine release, enhance leukocyte chemotaxis, and promote immune cell (including macrophages, neutrophils and T cells) infiltration into the CNS (Lin et al., 2014