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2.3.2 Other ferroptosis-associated axes Although GSH/GPX4, ACSL4, and PUFA are the main factors required for ferroptosis, exogenous oxygen radicals generated by photodynamic therapy (PDT) can directly peroxidize PUFAs and initiate lipid autoxidation, triggering ferroptosis-like cell death by means independent of LOXs and ACSL4 (53)

Discussion Dielectric barrier discharges in ambient air produce reactive oxygen and nitrogen species (RONS) 9 inducing numerous oxidative modifications in a variety of biomolecules 24,31