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In a randomized controlled trial that included 109 healthy men with mildly elevated cholesterol levels, 150 mg of aronia polyphenols daily for 90 days reduced total and LDL-cholesterol levels in men under 40 years of age, but not those 40 years and older, and had no effects on measures of glucose metabolism, blood pressure, oxidative stress, or inflammation

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In other words, it acts like an antioxidant

Because Nrf2 suppresses NF-B and downstream proinflammatory cytokines, its absence may result in more severe inflammation in astrocytes [127]