This is something I discuss with my patients routinely when they come in with questions about them. Stewart recommends patients stop taking GLP-1s for at least two to three months before trying to conceive, and before beginning infertility treatments
Waist circumference and waist-to-hip ratio provide supplementary tracking metrics
A recent meta-analysis of randomized controlled trials (RCTs), including AMPLITUDE-O, examining six GLP-1 receptor agonists (lixisenatide, liraglutide, subcutaneous semaglutide, exenatide, dulaglutide, and efpeglenatide) reported a 21% reduction in a composite kidney outcome (macroalbuminuria, doubling of serum creatinine or 40% eGFR decline, RRT, or death from kidney disease), corresponding to a number needed to treat of 47 [73]
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