C., Roberts, N., Branigan, H., Stanfield, A
One possible explanation is that low serum vitamin B12 levels would trap folate as 5-methyltetrahydrofolate, prevent the generation of methionine from homocysteine, and therefore reduce protein synthesis and lean tissue deposition
Unlike proteins, which are much longer chains of amino acids, peptides are small enough to trigger highly specific biological responses at the cellular level
Johns Wort (an herbal antidepressant), some opioid painkillers (like tramadol, meperidine), and even the anti-parkinson medication selegiline
If fatigue is severe or persistent, discussing alternative treatments with your doctor is advisable