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In preclinical models resistant to anti-PD-L1 treatment, dual blockade of IL-6R and PD-L1 attenuated tumour growth and improved survival [350, 351], leading to clinical evaluation of this combination therapy

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The resulting strain W303-1b/gsh1/F (F pathway) together with W303-1b/G (G pathway) and W303-1b/gsh1/pro1 (P pathway) represent different pathway strains (Table 2)

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Nutrients 11 (5), 1024