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Characterization of Heme as Activator of Toll-like Receptor 4 *

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Furthermore, epigenetic memories have been shown to persist in human adipose tissue, denoting incomplete recovery of metabolic function, and may explain the accelerated rebound obesity in individuals with subsequent exposure to obesogenic lifestyles, after substantial weight loss [163]

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11 Destruction of the entire vessel wall and not just the endothelium is necessary, as demonstrated in animal studies described later in this chapter

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