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Wang Y, Yen FS, Zhu XG, Timson RC, Weber R, Xing C, et al

This axis underscores the intertwined effects when either component declines and can be seen a feedback loop between telomere dysfunction and mitochondrial dysfunction

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116,117,118 Notably, several studies have shown that MeCP2 binds with chromatin and transcriptional activators at the promoter of an activated target to activate gene expression, which means that MeCP2 can operate as both an activator and a repressor of transcription

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