Guideline Approach to Therapy in Patients With Newly Diagnosed Type 2 Diabetes
Gonadorelin (GnRH) Primary uses: Testosterone support Fertility enhancement Maintaining testicular function during TRT Typical dosing: 100-200mcg, 2-3 times daily (pulsatile dosing) Duration: Ongoing alongside TRT if used for that purpose Administration: Subcutaneous injection Special notes: Requires frequent dosing (mimics natural GnRH pulses) Maintains natural hormone production Used in fertility treatments HCG (Human Chorionic Gonadotropin) Primary uses: Testosterone support Fertility (both male and female) Maintaining testicular size during TRT Weight loss (controversial) Typical dosing: 250-500 IU, 2-3 times per week Duration: Depends on purpose Administration: Subcutaneous or intramuscular injection Special notes: Prescription medication Mimics LH (luteinizing hormone) Well-established safety profile Banned by WADA DSIP (Delta Sleep-Inducing Peptide) Primary uses: Sleep quality Stress reduction Pain management Typical dosing: 100-300mcg before bed Duration: As needed for sleep support Administration: Subcutaneous injection Special notes: Mixed evidence for effectiveness Some users report excellent sleep Others notice minimal effects Very safe with no dependence Vasoactive Intestinal Peptide (VIP) Primary uses: Mold toxicity treatment Immune regulation Inflammatory conditions Typical dosing: 50mcg, 4 times daily Intranasal spray Duration: 4-12 months for mold illness Administration: Intranasal spray (not injectable typically) Special notes: Specialized use for biotoxin illness Prescribed by mold-literate physicians Expensive Requires proper diagnosis How to choose the right injectable peptide With so many options, selection requires strategy
Wan R, Wang L, Duan Y, Zhu M, Li W, Zhao M, et al
Sharing a 94% structural homology with native human GLP-1, Semaglutide is distinguished by three modifications: 1) amino-acid substitutions at position 8 (alanine to -aminoisobutyric acid or Aib) and position 34 (lysine to arginine), and acylation of the lysine in position 26 with a spacer consisting of two 8-amino-3,6-dioxaoctanoic acid (ADO) moieties, a glutamic acid moiety, and a C-18 fatty di-acid side chain (Lau et al., 2015)
Changes in Metabolism Help Melanomas Spread Melanoma, the deadliest form of skin cancer, can be treated effectively through surgery when its caught early
